Published by MD Magazine

Neuropathic pain may be reduced when patients take antidepressants that alter a brain pathway, according to findings published in the Proceedings of the National Academy of Sciences (PNAS).   Researchers from The Mount Sinai Hospital used mice models with chronic neuropathic pain in order to demonstrate the abilities of common antidepressants to counter both pain and depression related symptoms. The researchers built this study around prior research, which demonstrated that pain often leads to depression. In those studies, tricyclic antidepressants (TCA) and selective serotonin norepinephrine inhibitors (SNRIs) were used to effectively counter pain and depression related symptoms.

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