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With the Memorial Day Weekend upon us, I thought it would be a great opportunity to remind patients requiring regular use of opioid therapy, to avoid alcohol as they celebrate and reflect on the sacrifices of heroic veterans past and present, that enable us to celebrate freely.

That said, I recruited our current PGY1 Resident, Dr. Amanda Mogul to revisit an important drug interaction that has unfortunately led to harm or death among opioid-requiring patients. Here’s what she had to say…

In 2010, the National Vital Statistics System reported that opioids were responsible 75.2% of all overdose deaths in the United States.1 Of these deaths, 30.1% also involved benzodiazepines. The risk of concomitant opioids and benzodiazepines has been addressed and well documented in the medical literature. However, what providers and patients often do not realize is the exponential increase in risk when adding the skeletal muscle relaxant carisoprodol (Soma) into the mix.

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